Glial scar - Wikipedia
A glial scar formation (gliosis) is a reactive cellular process involving astrogliosis that occurs after injury to the central nervous system. As with scarring in other organs and tissues, the glial scar …
The diversity and disparity of the glial scar - Nature
Dec 21, 2017 · The glial scar is made up of reactive astrocytes (orange), NG2 glia (teal) and microglia (purple) that form a tight barrier around the lesion core, or area of severe tissue …
Moving beyond the glial scar for spinal cord repair - Nature
Aug 28, 2019 · While traditionally referred to as a glial scar, the spinal injury scar in fact comprises multiple cellular and extracellular components. This multidimensional nature should …
Portrait of glial scar in neurological diseases - PMC
In central nervous system (CNS), glial scar grows as a major physical and chemical barrier against regeneration of neurons as it forms dense isolation and creates an inhibitory …
Understanding the Role of the Glial Scar through the Depletion of Glial …
The glial scar is a compact mesh structure that surrounds the CNS lesions rapidly after the initial damage and is fully formed between two and three weeks post-injury (wpi) in rodents. This …
The soft mechanical signature of glial scars in the central nervous ...
Mar 20, 2017 · Mammalian glial scars supposedly form a chemical and mechanical barrier to neuronal regeneration. While tremendous effort has been devoted to identifying molecular …
The diversity and disparity of the glial scar - PMC
The glial scar is made up of reactive astrocytes (orange), NG2 glia (teal) and microglia (purple) that form a tight barrier around the lesion core, or area of severe tissue damage. The lesion …
Glial function (and dysfunction) in the normal & ischemic brain
Glial scars are thought to form a barrier function to contain released toxic substances and inflammatory cells but at the same time impair axon regeneration through the expression of …
The diversity and disparity of the glial scar - PubMed
One such response, the glial scar, is a structural formation of reactive glia around an area of severe tissue damage. While traditionally viewed as a barrier to axon regeneration, beneficial …
Glial Scar - SpringerLink
Jan 1, 2024 · The term glial scar describes the structure that develops at regions of CNS injury. Macroscopically, a region of pale tissue that looks similar to scar tissue in the skin or …