along with mouse embryonic stem cells, they introduced a traceable version of netrin1 to the developing spinal cord to ...

Sandhoff and Tay-Sachs diseases cause progressive damage to nerve cells in the brain and spinal cord. There is currently no ...

Model used to create a cellular 'hologram' of a mouse embryo could be used to visualize development in any species.

Multiple sclerosis, a neuroinflammatory disease that affects nearly 3 million people worldwide, causes a loss of myelin, the ...

Key takeawaysUCLA researchers have uncovered a surprising new role for netrin1, a crucial protein in neural development, as a ...

In a groundbreaking study, researchers at McMaster University have identified a potential treatment for Sandhoff and Tay-Sachs diseases—two rare, often fatal lysosomal storage disorders that cause ...

A large interdisciplinary team of researchers has found that as mice age, levels of a certain type of immunoglobulin escalate ...

Researchers have found a process by which the brain guards against attack by the immune system. In mice with multiple sclerosis, such 'guardian' proteins that train the immune system were drastically ...

To investigate these processes, the researchers used spatial transcriptomics to create maps of nine tissues – hippocampus, ...

Multiple sclerosis (MS) is a debilitating disease of the brain and spinal cord that impacts millions worldwide.