Hantavirus Replication Cycle—An Updated Structural Virology …
WEBAug 6, 2021 · In this review, we summarize our current understanding of the molecular and structural biology of the hantavirus replication cycle, focusing on recent insights from structural virology studies. We discuss somewhat contradictory hypotheses regarding hantavirus entry, replication, and assembly.
HantaNet: A New MicrobeTrace Application for Hantavirus
WEBNov 2, 2023 · HantaNet integrates coding gene sequences and standardized metadata from hantavirus reference genomes into three separate gene modules for dashboard visualization of phylogenetic trees, viral strain clusters for classification, epidemiological networks and spatiotemporal analysis.
Hantavirus entry: Perspectives and recent advances - PMC
WEBHantaviruses are important zoonotic pathogens of public health importance that are found on all continents except Antarctica and are associated with hemorrhagic fever with renal syndrome (HFRS) in the Old World and hantavirus pulmonary …
Hantaviruses - PMC - National Center for Biotechnology Information
WEBIn 1981, Hantaan virus strain 76-118, isolated from Apodemus agrarius was grown in A549 cell line, and its electron microscopic images revealed that the virus was a new member of the Bunyaviridae family.
Epidemiology and diagnosis of hantavirus infections - UpToDate
WEBApr 17, 2024 · The epidemiology and diagnosis of hantavirus infections, with a special emphasis on HCPS, will be reviewed here. The clinical manifestations, pathogenesis, and prevention of hantavirus infection are discussed separately.
Uncovering the mysteries of hantavirus infections - Nature
WEBJul 16, 2013 · Hantaviruses are negative-sense single-stranded RNA viruses that infect many species of rodents, shrews, moles and bats. Hantaviruses primarily replicate in the endothelium and might use...
The Hantavirus Surface Glycoprotein Lattice and Its Fusion …
WEBSep 15, 2020 · X-ray structures of the hantavirus surface glycoprotein lattice reveal a built-in mechanism controlling envelope glycoprotein membrane insertion and provide important information for development of immunogen protection against these deadly viruses.
Hantavirus diseases pathophysiology, their diagnostic strategies and ...
WEBThis review has been compiled to provide a comprehensive overview of hantaviruses disease, its pathophysiology, diagnostic tools and the treatment approaches to control the hantavirus infection.
Hantavirus Replication Cycle-An Updated Structural Virology
WEBAug 6, 2021 · In this review, we provide an update on the hantavirus replication cycle with a special focus on structural virology aspects. Keywords: X-ray crystallography; cryo-electron microscopy; cryo-electron tomography; hantaviruses; structural virology; viral fusion glycoproteins; viral genome encapsidation; viral replication; viral transcription ...
Structural characterization of the oligomerization of full-length ...
WEBMar 13, 2024 · Hantaan virus is a dangerous human pathogen whose segmented negative-stranded RNA genome is replicated and transcribed by a virally-encoded multi-functional polymerase. Here we describe the...
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